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Grants due in October 2027

35 open grants close in October 2027, 28 of them open to small businesses. Every listing links to its official source.

October 2027

Friday, October 1 1 deadline

Home Study and Post-Release Services for Unaccompanied Alien Children

Department of Health and Human Services $1M to $100M Small businesses eligible

Closes Oct 1, 2027

Monday, October 4 1 deadline

BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies (U01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Oct 4, 2027

Thursday, October 7 1 deadline

Advanced Technological Education (ATE)

U.S. National Science Foundation $475K to $7.5M Others (see eligibility details)

Closes Oct 7, 2027

Friday, October 8 2 deadlines

Translational Efforts to Advance Gene-based Therapies for Ultra-Rare Neurological and Neuromuscular Disorders (U01 - Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Oct 8, 2027
Utilizing the PLCO Biospecimens Resource to Bridge Gaps in Cancer Etiology and Early Detection Research (U01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Oct 8, 2027

Tuesday, October 12 1 deadline

NIDCD Research Grants for Translating Basic Research into Clinical Practice (R01 Clinical Trial Optional)

Department of Health and Human Services Up to $500K Small businesses eligible

Closes Oct 12, 2027

Wednesday, October 13 1 deadline

Research Experiences for Teachers (RET) in Engineering and Computer Science

U.S. National Science Foundation From $600K Others (see eligibility details)

Closes Oct 13, 2027

Thursday, October 14 2 deadlines

NCI Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Oct 14, 2027
NCI Pathway to Independence Award (K99/R00 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Oct 14, 2027

Friday, October 15 11 deadlines

Confirmatory Efficacy Clinical Trials of Non-Pharmacological and Pharmacological Interventions for Mental Disorders (R01 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Oct 15, 2027
Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R33 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Oct 15, 2027
Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Oct 15, 2027
Early Stage Testing of Pharmacologic or Neuromodulatory Device-based Interventions for the Treatment of Mental Disorders (R33- Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Oct 15, 2027
Early Stage Testing of Pharmacologic or Neuromodulatory Device-based Interventions for the Treatment of Mental Disorders (R61/R33 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Oct 15, 2027
Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Oct 15, 2027
First in Human and Early Stage Clinical Trials of Novel Investigational Drugs or Neuromodulatory Device-based Interventions for Psychiatric Disorders (U01 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Oct 15, 2027
Full-Scale Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 - Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Oct 15, 2027
NIDCD Early Career Research(ECR) Award (R21 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Oct 15, 2027
NSF Astronomy and Astrophysics Postdoctoral Fellowships (AAPF)

U.S. National Science Foundation From $110K Others (see eligibility details)

Closes Oct 15, 2027
Pilot Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Oct 15, 2027

Saturday, October 16 1 deadline

NEI Research Grant for Vision-Related Secondary Data Analysis (R21 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Oct 16, 2027

Monday, October 18 1 deadline

NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders (U01 - Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Oct 18, 2027

Tuesday, October 19 3 deadlines

Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)

Department of Health and Human Services $50K to $300K Small businesses eligible

Closes Oct 19, 2027
Historically Black Colleges and Universities - Excellence in Research (HBCU - EiR)

U.S. National Science Foundation Others (see eligibility details)

Closes Oct 19, 2027
Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional)

Department of Health and Human Services Up to $650K Public and state-controlled colleges

Closes Oct 19, 2027

Wednesday, October 20 4 deadlines

Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Neurotherapeutic Agent Identification (R61/R33 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $750K Small businesses eligible

Closes Oct 20, 2027
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $750K Small businesses eligible

Closes Oct 20, 2027
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies (R61/R33 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Oct 20, 2027
Mathematical Sciences Postdoctoral Research Fellowships (MSPRF)

U.S. National Science Foundation From $190K Others (see eligibility details)

Closes Oct 20, 2027

Monday, October 25 5 deadlines

Cancer Prevention and Control Clinical Trials Planning Grant Program (R34 Clinical Trials Optional)

Department of Health and Human Services Small businesses eligible

Closes Oct 25, 2027
Cancer Prevention and Control Clinical Trials Planning Grant Program (U34 Clinical Trials Optional)

Department of Health and Human Services Small businesses eligible

Closes Oct 25, 2027
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U01 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Oct 25, 2027
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U19 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Oct 25, 2027
Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required)

Department of Health and Human Services Up to $375K Public and state-controlled colleges

Closes Oct 25, 2027

Thursday, October 28 1 deadline

Mechanistic Evaluation of Therapeutic Targets derived from Treatable Traits to Improve CNS Outcomes in People with HIV (R21/R33 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Oct 28, 2027