Department of Health and Human Services, National Institutes of Health
Mechanistic Toxicology of METALS: Metal Exposure, Transport, Action, Localization, and Susceptibility (RP1 Clinical Trial Not Allowed)
Who can apply
- Public and tribal housing authorities
- Nonprofits without 501(c)(3) status
- County governments
- City or township governments
- Federally recognized tribal governments
- Others (see eligibility details)
- Tribal organizations
- Independent school districts
- Small businesses
- State governments
- Private colleges and universities
- Special district governments
- Nonprofits with 501(c)(3) status
- For-profit organizations (not small businesses)
- Public and state-controlled colleges
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;
About this grant
The purpose of this funding opportunity is to support mechanistic research to understand how exposure to metals and metal-containing compounds alters biological processes relevant to human health. Of particular interest are studies that elucidate the absorption, distribution, transport, cellular trafficking, biological interactions, and mechanisms of action of metals, including mechanisms through which metals may alter immune homeostasis, cross the placental barrier, or gain access to and affect the central nervous system. Studies may employ experimental models, new approach methodologies, computational approaches, or leverage human biospecimens where these approaches are used to address defined mechanistic hypotheses.
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