Department of Health and Human Services, National Institutes of Health
NIH Director's Transformative Research Award (R01 Clinical Trial Optional)
Who can apply
- Federally recognized tribal governments
- Nonprofits without 501(c)(3) status
- Special district governments
- Small businesses
- Nonprofits with 501(c)(3) status
- Tribal organizations
- Private colleges and universities
- County governments
- Independent school districts
- Public and tribal housing authorities
- Others (see eligibility details)
- City or township governments
- Public and state-controlled colleges
- State governments
- For-profit organizations (not small businesses)
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
About this grant
The NIH Director's Transformative Research Award supports individual scientists and research teams pursuing bold, groundbreaking, and unconventional research with the potential to transform science, create new scientific paradigms, establish new clinical approaches, or develop transformative technologies. The Transformative Research Award is part of the NIH Common Fund's High-Risk, High-Reward Research Program.
Who has won this before
Assistance Listing 93.310
5,131awards with funding activity in the last 3 completed federal fiscal years, 2024–2026 (October 1, 2023 to September 30, 2026). Total awarded during this period: $3,182,829,988.35 in net obligations (funding committed, less reductions).
These awards are for the Assistance Listing as a whole, which may cover multiple opportunities.
Largest recent recipients, ranked by total award amount. Amounts below may include funding outside this period; years are award start years.
- UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL$976,983,003.37Place of performance: North CarolinaStarted
- FRED HUTCHINSON CANCER CENTER$383,462,828.81Place of performance: WashingtonStarted
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI$250,012,117.44Place of performance: New YorkStarted
- DANA-FARBER CANCER INSTITUTE, INC.$235,803,541Place of performance: MassachusettsStarted
- OREGON HEALTH & SCIENCE UNIVERSITY$203,025,735Place of performance: OregonStarted
Most awards went to California, Massachusetts, and New York, ranked by dollars obligated at the place of performance across all matching awards.
Past rounds of this program (93.310)
Checked .
Award data from USAspending.gov.
Program history
Topics
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