Arthritis, Musculoskeletal and Skin Diseases Research (93.846)

National Institutes of Health

Opened 8 times since 2025. Usually posted in June, with deadlines in December.

Based on 8 recorded past opportunities. Opportunities under one Assistance Listing may cover different projects or funding cycles.

When might the next round open?

Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional): expected to open November 5, 2026, according to the current forecast.
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional): expected to open November 5, 2026, according to the current forecast.
NIAMS Clinical Trial Implementation Cooperative Agreement: expected to open November 2, 2026, according to the current forecast.

Open now

Forecast opportunities are expected but are not accepting applications yet.

HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes in 6 days
Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes in 9 days
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes in 9 days
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)

Department of Health and Human Services Up to $375K Others (see eligibility details)

Closes in 30 days
Restoring Joint Health and Function to Reduce Pain (RE-JOIN) 2.0

Department of Health and Human Services Small businesses eligible

Expected around Dec 1
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Dec 4
Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Expected around Jan 5, 2027
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Expected around Jan 5, 2027
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2027
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)

Department of Health and Human Services Up to $350K Small businesses eligible

Closes Jan 15, 2027
Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)

Department of Health and Human Services Up to $500K Nonprofits eligible

Closes Jan 27, 2027
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases

Department of Health and Human Services $300K to $600K Small businesses eligible

Expected around Mar 4, 2027
NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Mar 4, 2027
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Apr 5, 2027
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Apr 5, 2027
Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Apr 18, 2027
Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 8, 2027
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes May 8, 2027
NIAMS Clinical Trial Implementation Cooperative Agreement

Department of Health and Human Services From $250K Small businesses eligible

Expected around Jul 2, 2027
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jul 12, 2027
Successor-in-Interest (Type 6 Parent Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jul 17, 2027
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Sep 7, 2027
Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional)

Department of Health and Human Services Up to $650K Public and state-controlled colleges

Closes Oct 19, 2027
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $375K Others (see eligibility details)

Closes Jan 7, 2028
Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2028
Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2028
Limited Competition: CCRP Initiative: Promoting a Basic Understanding of Chemical Threats to Skin (R34 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2028
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2028
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2028
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2028
NIH Research Project Grant (Parent R01 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2028
Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $375K Private colleges and universities

Closes Jan 7, 2028
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32)

Department of Health and Human Services Small businesses eligible

Closes May 4, 2028
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2028
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2028
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2028
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2028
INCLUDE Project: Clinical Trials Phased Awards for Down syndrome Research (R61/R33 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Jun 15, 2028
INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $200K Small businesses eligible

Closes Jun 15, 2028
INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $500K Small businesses eligible

Closes Jun 15, 2028
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Aug 25, 2028
Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $100K Public and state-controlled colleges

Closes Sep 7, 2028
Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed)

Department of Health and Human Services Up to $125K Private colleges and universities

Closes Sep 7, 2028
Development of Candidate Medical Countermeasures (MCMs) and Technologies Against Radiological/Nuclear or Chemical Threats (U01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Oct 9, 2028
CCRP Initiative: Promoting a Basic Understanding of Chemical Threats to Skin (R01 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $300K Small businesses eligible

Closes Nov 5, 2028
Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Nov 30, 2028
Limited Competition: Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed)

Department of Health and Human Services $25K to $250K Small businesses eligible

Closes Jan 26, 2029
HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Feb 20, 2029
NIAMS P30 Centers Program (P30 - Clinical Trial Not Allowed)

Department of Health and Human Services Up to $500K Small businesses eligible

Closes Mar 1, 2029
SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Apr 5, 2029
Predoctoral to Postdoctoral Transition Award (Parent F99/K00 - Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Apr 8, 2029
NIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2029
Implementation Science to Advance HIV Prevention, Treatment, and Care (R61/R33 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jun 20, 2029
Limited Competition: Small Grant Program for Mentored Research Career Development Award Recipients (R03) (Clinical Trials Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jul 16, 2029
Collaborative Program Grant for Interdisciplinary Teams (RM1 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Sep 26, 2029

Past rounds

HEAL INITIATIVE: INTERACT Data Coordination and Integration Center (U24 Clinical Trial Not Allowed)

RFA-AR-27-002

Posted
May 19, 2026

Deadline
October 1, 2026

Award
Not listed
Accelerating Product Excellence in Innovation and for Clinical Adoption (APEx) (U24 Clinical Trial Not Allowed)

RFA-DE-27-002

Posted
May 4, 2026

Deadline
July 10, 2026

Award
Up to $4M
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required)

PAR-25-323

Posted
August 25, 2025

Deadline
May 24, 2026

Award
Not listed
Limited Competition: Regenerative Medicine Innovation Project (RMIP) Investigator-Initiated Clinical Trials (UH3 Clinical Trial Optional)

RFA-AR-25-014

Posted
June 17, 2025

Deadline
December 9, 2025

Award
Not listed
Limited Competition: Regenerative Medicine Innovation Project (RMIP) Investigator-Initiated Studies (U01 Clinical Trial Not Allowed)

RFA-AR-25-013

Posted
June 17, 2025

Deadline
December 9, 2025

Award
Not listed
Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional)

PAR-25-438

Posted
June 5, 2025

Deadline
December 9, 2025

Award
Up to $1M
Multidisciplinary Studies of HIV/AIDS and Aging (R21 Clinical Trial Optional)

PAR-25-355

Posted
January 8, 2025

Deadline
January 8, 2026

Award
Not listed
Multidisciplinary Studies of HIV/AIDS and Aging (R01 Clinical Trial Optional)

PAR-25-354

Posted
January 8, 2025

Deadline
January 8, 2026

Award
Not listed

History from Grants.gov, checked October 24, 2026 at 2:32 PM CT.

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